In San Antonio, TX, Registered Nurses earn a median of $83,740 a year — about 11% below the U.S. median of $94,480. Among the 50 metros tracked here for this role, that ranks #30.
What that pay is worth in San Antonio
Local prices run 95 on the BEA cost-of-living index (U.S. = 100), so a $88,880 salary stretches further than the sticker number — about $93,838 in national-average buying power.
Can Registered Nurses afford a home in San Antonio?
A typical San Antonio home runs about $219,700 — 2.5 times the average Registered Nurse salary, very affordable against the classic 3x rule of thumb. Median rent near $1,258/mo takes roughly 17% of gross pay — within the 30% comfort line.
The Registered Nurse pay ladder in San Antonio
Entry-level (10th percentile) Registered Nurses earn about $63,480; the top 10% reach $108,660 — a $45,180 spread, moderate for this field. Most of that gap comes down to experience, employer, and how hard you negotiate.
The Registered Nurse job market in San Antonio
San Antonio employs roughly 22,140 Registered Nurses. It’s a sizable local market to build a career in.
Compare San Antonio with other cities
See the full Registered Nurse salary by city ranking to weigh San Antonio against the other metros on both pay and cost-adjusted value, or use the cost-of-living calculator to compare any two cities directly.
Frequently asked questions
How much do Registered Nurses make in San Antonio?
The average Registered Nurse in San Antonio, TX earns about $88,880 per year, 5.9% below the national average of $94,480.
What is the take-home pay for Registered Nurses in San Antonio after taxes?
After federal and TX taxes, this $88,880 salary is worth about $71,357 a year - roughly $5,946 a month in take-home pay, an effective tax rate near 20%.
What do the highest-paid Registered Nurses earn in San Antonio?
The top 10% of Registered Nurses in San Antonio earn about $108,660 a year, versus about $63,480 for the bottom 10%.
Can Registered Nurses afford a home in San Antonio?
A typical San Antonio home runs about $219,700 - roughly 2.5x this salary, within reach by the classic 3x rule of thumb.