Average Registered Nurse Salary in Mesa, AZ

The average Registered Nurse in Mesa, AZ earns $92,540 per year. See how this compares to the national average and what it means for your budget.

Average Salary
$92540
Median Salary
$89390
vs. National
2.1% below
Real Pay (COL-adjusted)
$89570

“Real pay” adjusts the average for Mesa’s cost of living (Regional Price Parity 103.316, U.S. average = 100) — what this salary is worth in national-average dollars.

What Registered Nurses actually earn in Mesa

The spread from entry-level (10th percentile) to top earners (90th), from BLS wage data.

10th (entry) $71230
25th $81350
Median $89390
75th $103450
90th (top) $111400

46350 Registered Nurses employed in the Mesa metro.

What’s this salary worth in another city?

What you earn (or want to compare)

Take-home pay for a Registered Nurse in Mesa

Estimated pay after federal, FICA, and AZ state taxes (2026). Prefilled with the local average — adjust for your situation.

Estimate only — not tax advice. Tax year 2026, federal + FICA + state (single or married filing jointly). Excludes local/city income taxes (e.g., NYC, Philadelphia) and individual credits. See our methodology.

Mesa at a glance

Cost of living (RPP, U.S.=100)103.316

In Mesa, AZ, Registered Nurses earn a median of $89,390 a year — about 5% below the U.S. median of $94,480. Among the 50 metros tracked here for this role, that ranks #22.

What that pay is worth in Mesa

Local prices run 103 on the BEA cost-of-living index (U.S. = 100), so a $92,540 salary buys less than it looks — about $89,570 in national-average buying power.

The Registered Nurse pay ladder in Mesa

Entry-level (10th percentile) Registered Nurses earn about $71,230; the top 10% reach $111,400 — a $40,170 spread, moderate for this field. Most of that gap comes down to experience, employer, and how hard you negotiate.

The Registered Nurse job market in Mesa

Mesa employs roughly 46,350 Registered Nurses. It’s a sizable local market to build a career in.

Compare Mesa with other cities

See the full Registered Nurse salary by city ranking to weigh Mesa against the other metros on both pay and cost-adjusted value, or use the cost-of-living calculator to compare any two cities directly.

Frequently asked questions

How much do Registered Nurses make in Mesa?

The average Registered Nurse in Mesa, AZ earns about $92,540 per year, 2.1% below the national average of $94,480.

What is the take-home pay for Registered Nurses in Mesa after taxes?

After federal and AZ taxes, this $92,540 salary is worth about $71,827 a year - roughly $5,985 a month in take-home pay, an effective tax rate near 22%.

What do the highest-paid Registered Nurses earn in Mesa?

The top 10% of Registered Nurses in Mesa earn about $111,400 a year, versus about $71,230 for the bottom 10%.

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