Average Registered Nurse Salary in Denver, CO

The average Registered Nurse in Denver, CO earns $93,190 per year. See how this compares to the national average and what it means for your budget.

Average Salary
$93190
Median Salary
$87330
vs. National
1.4% below
Real Pay (COL-adjusted)
$88096

“Real pay” adjusts the average for Denver’s cost of living (Regional Price Parity 105.782, U.S. average = 100) — what this salary is worth in national-average dollars.

What Registered Nurses actually earn in Denver

The spread from entry-level (10th percentile) to top earners (90th), from BLS wage data.

10th (entry) $71560
25th $80400
Median $87330
75th $104750
90th (top) $116680

29460 Registered Nurses employed in the Denver metro.

Can a Registered Nurse afford a home in Denver?

Max home price under the 28% rule (housing ≤ 28% of gross), 10% down, 6.7% 30-yr rate. Median Denver home: $586700.

Earnings levelSalaryMax homeMedian home?
Entry (10th)$71560$28751349%
Median$87330$35087460%
Top (90th)$116680$46879680%

What’s this salary worth in another city?

What you earn (or want to compare)

Take-home pay for a Registered Nurse in Denver

Estimated pay after federal, FICA, and CO state taxes (2026). Prefilled with the local average — adjust for your situation.

Estimate only — not tax advice. Tax year 2026, federal + FICA + state (single or married filing jointly). Excludes local/city income taxes (e.g., NYC, Philadelphia) and individual credits. See our methodology.

Denver at a glance

Population713734
Median household income$91681
Median home value$586700
Median rent$1770/mo
Cost of living (RPP, U.S.=100)105.782
Bachelor’s degree or higher33.8%
Poverty rate11%

In Denver, CO, Registered Nurses earn a median of $87,330 a year — about 8% below the U.S. median of $94,480. Among the 50 metros tracked here for this role, that ranks #26.

What that pay is worth in Denver

Local prices run 106 on the BEA cost-of-living index (U.S. = 100), so a $93,190 salary buys less than it looks — about $88,096 in national-average buying power.

Can Registered Nurses afford a home in Denver?

A typical Denver home runs about $586,700 — 6.3 times the average Registered Nurse salary, a stretch against the classic 3x rule of thumb. Median rent near $1,770/mo takes roughly 23% of gross pay — within the 30% comfort line.

The Registered Nurse pay ladder in Denver

Entry-level (10th percentile) Registered Nurses earn about $71,560; the top 10% reach $116,680 — a $45,120 spread, moderate for this field. Most of that gap comes down to experience, employer, and how hard you negotiate.

The Registered Nurse job market in Denver

Denver employs roughly 29,460 Registered Nurses. It’s a sizable local market to build a career in.

Compare Denver with other cities

See the full Registered Nurse salary by city ranking to weigh Denver against the other metros on both pay and cost-adjusted value, or use the cost-of-living calculator to compare any two cities directly.

Frequently asked questions

How much do Registered Nurses make in Denver?

The average Registered Nurse in Denver, CO earns about $93,190 per year, 1.4% below the national average of $94,480.

What is the take-home pay for Registered Nurses in Denver after taxes?

After federal and CO taxes, this $93,190 salary is worth about $70,997 a year - roughly $5,916 a month in take-home pay, an effective tax rate near 24%.

What do the highest-paid Registered Nurses earn in Denver?

The top 10% of Registered Nurses in Denver earn about $116,680 a year, versus about $71,560 for the bottom 10%.

Can Registered Nurses afford a home in Denver?

A typical Denver home runs about $586,700 - roughly 6.3x this salary, a stretch by the 3x rule, so budgeting discipline matters.

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